Nephropathy

ShannonB Model

Latest Release: 15. October 2018

Latest Version: PROSIT Nephropathy Type 2 Diabetes Disease Model 2018B Germany

Summary: Shannon B: first release of the Danube B structure based on the Shannon A methodology with updated inputs. The model is open for discussion: use the discussion link at the top of this page.

Methodology: Markov model (Markov process)

Health Economic Perspective: flexible, dependent on user specification

Time Horizon: 80 cycles; currently defined as annual time steps

Patient Cohort: realistic diabetes cohort for Germany and type 2 diabetes mellitus based on the ProValue study. Divided into up to 16 sub-cohorts. Cohort specifications can be edited freely.

Costs: summary costs for Germany are included based on the KODIM Cost study and results being inflationed to the year 2015. Costs can be edited freely.

Other specifications: the model supports QALYS, and discounting of both costs and effects. The half-cycle correction is implemented as within-cycle correction.

Team Members: Fabian Sailer, Monika Pobiruchin, Jonathan Schwarz, Wendelin Schramm

Previous Versions: PROSIT Nephropathy Type 2 Diabetes Disease Model 2016B Germany (from 11. July 2017)

Structure of the PROSIT Nephropathy Diabetes Disease Model nick named "Shannon B".

ShannonA Model

This model version has been replaced by the Shannon B model and is not supported any more since 2017.

Latest Release: October 2012

Latest Version: PROSIT Nephropathy Type 2 Diabetes Disease Model 2012A Germany RC1

Summary: Shannon A: New release of the Danube A structure based on a new methodology that allows to include patient sub-groups. The Release Candidates are open for discussion: use the discussion link at the top of this page.

Team Members: Christian Weiß, Jens Attumalil, Selcan Ipek, Keno März, Monika Pobiruchin, Wendelin Schramm

DanubeB Model

This model version has been replaced by the Shannon A model and is not supported any more since 2012.

Discontinued Danube B Version: The version below is based on the pre 2012 modelling procedures and has been abandoned.

Summary: Introduction of an additional transition from macroalbuminuria to microalbuminuria to the Danube A structure.

Team Members: SL, Wendelin Schramm

DanubeA Model

This model version has been replaced by the Danube B model and is not supported any more since 2010.

Structure of the PROSIT Nephropathy Diabetes Disease Model 2008A, nick named as Danube A. The Shannon A model and the Danube A model have the same structure but different approaches of implemenation.

Last Release: 08.01.2008

Last Version: PROSIT NEPHROPATHY TYPE 2 DIABETES DISEASE MODEL 2008A Germany RC1

Summary: n.a.

Team Members: Natalie Krämer, Sabrina Lang, Monika Pobiruchin, Michael Schöll, Wendelin Schramm, Björn Schreiweis, Benjamin Trinczek, Christian Weber

Structure of the PROSIT Nephropathy Diabetes Disease Model 2008A, nick named as Danube A. The Shannon A model and the Danube A model have the same structure but different approaches of implemenation.