Coronary Heart Disease Models
MissouriB Model
Latest Release: 14.10.2018
Latest Version: PROSIT Coronary Heart Disease Model 2018B Germany - Release Candidate
Summary: New release of the cardiovascular disease model based on a similar methodology as Missouri A that allows to include patient sub-groups.
Methodology: Markov model (Markov process)
Health Economic Perspective: flexible, dependent on user specification
Time Horizon: 80 cycles; currently defined as annual time steps
Patient Cohort: realistic diabetes cohort for Germany and type 2 diabetes mellitus based on the ProValue study. Divided into up to 16 sub-cohorts. Cohort specifications can be edited freely.
Costs: summary costs for Germany are included based on the KODIM Cost study and results being inflationed to the year 2015. Costs can be edited freely.
Other specifications: the model supports QALYS, and discounting of both costs and effects. The half-cycle correction is implemented as within-cycle correction.
Team Members: Fabian Sailer, Monika Pobiruchin, Wendelin Schramm
Previous Versions: PROSIT CHD Type 2 Diabetes Disease Model 2016B Germany (from 28. September 2017)

MissouriA Model
Discontinued version MissouriA: Missouri A has been abandoned with the release of the Missouri B model.
Latest Version: PROSIT Coronary Heart Disease Model 2013A Germany - RC1
Summary: First release of the MIssouri A structure based on a new methodology that allows to include patient sub-groups.
Team Members: Christian Weiß, Kurt Neeser, Jens Attumalil, Wendelin Schramm
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