​Coronary ​Heart Disease Models 

MissouriB Model  

Latest Release: 14.10.2018

Latest Version: PROSIT Coronary Heart Disease Model 2018B Germany - Release Candidate

Summary: New release of the cardiovascular disease model based on a similar methodology as Missouri A that allows to include patient sub-groups.

Methodology: Markov model (Markov process)

Health Economic Perspective: flexible, dependent on user specification

Time Horizon: 80 cycles; currently defined as annual time steps

Patient Cohort: realistic diabetes cohort for Germany and type 2 diabetes mellitus based on the ProValue study. Divided into up to 16 sub-cohorts. Cohort specifications can be edited freely. 

Costs: summary costs for Germany are included based on the KODIM Cost study and results being inflationed to the year 2015. Costs can be edited freely. 

Other specifications: the model supports QALYS, and discounting of both costs and effects. The half-cycle correction is implemented as within-cycle correction.

Team Members: Fabian Sailer, Monika Pobiruchin, Wendelin Schramm

Previous Versions: PROSIT CHD Type 2 Diabetes Disease Model 2016B Germany (from 28. September 2017) 

Structure of the PROSIT Myocardial Infarction Diabetes Disease Model Missouri A/B

MissouriA Model  

Discontinued version MissouriA: Missouri A has been abandoned with the release of the Missouri B model. 

Latest Version: PROSIT Coronary Heart Disease Model 2013A Germany - RC1

Summary: First release of the MIssouri A structure based on a new methodology that allows to include patient sub-groups. 

Team Members: Christian Weiß, Kurt Neeser, Jens Attumalil, Wendelin Schramm

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